Actavis Diazepam is a benzodiazepine drug that works on conditions such as anxiety, symptoms caused or related to withdrawal of alcohol like tremors or agitations, and adjacent treatment for some seizure types & spasms of skeletal spasms. In some cases, it is also used with other combinations as well. Actavis Diazepam is available in below strengths; 2 mg/5 mg/10mg.
Actavis Diazepam belongs to the group of long-acting benzodiazepine and has some anticonvulsant properties. It has zero effect on the GABA levels and glutamate decarboxylase activity. However, it has a minimal effect on the gamma-aminobutyric acid transaminase activity. Like other benzodiazepine drugs such as clonazepam and flurazepam, it also acts via the binding sites of a micromolar benzodiazepine as Ca2+ channel blockers. It also inhibits the depolarization-sensitive Calcium Uptake in the preparations of rat nerve cell, significantly.
Actavis Diazepam is prescribed in the treatment of insomnia, anxiety, panic attacks, and symptoms related to acute alcohol withdrawal. It also has uses as a vital premedication for anxiolysis, inducing sedation, and amnesia prior to some medical procedures such as endoscopy. It can also be prescribed as a treatment for benzodiazepine dependence because it has long half-life that helps in easier reduction of doses. There will be low toxicity in cases of overdose.
Administration and Dosage
Dosage should be recommended by the physician for optimum beneficial effect. There will be cases where the patient may need higher dosages. In those cases, the physician will decide the frequency and strength of the medication. However, while increasing the doses the physician should be cautious and should try to avoid the adverse effects.
Use of Actavis Diazepam is contraindicated mainly in patients with the following conditions.
• Liver disorders
• Severe hypoventilation
• Acute & narrow-angle glaucoma
• Severe or moderate hepatic deficiencies
• Severe or moderate renal deficiencies
• Severe or moderate sleep apnea
• Breast-feeding or pregnancy
• Shock or coma
• Allergy to any benzodiazepine drugs
• History of drug dependence or alcohol
• Myasthenia gravis
• Debilitated or elderly patients
• Abrupt or sudden discontinuation of the therapy
• Severe depression
• Acute intoxication (narcotics, alcohol etc.)
The adverse effects of this friginclude confusion and anterograde amnesia if given in higher doses. There can also be a little sedation. The elderly patients are likely to suffer few adverse effects such as ataxia, amnesia, confusion, hangover effects, and falls. Long-term use can result in benzodiazepine dependence, benzodiazepine withdrawal syndrome, and drug tolerance.
Overdose of Actavis Diazepam will display one or multiple of the following symptoms.
• Mental Confusion
• Impaired motor functions (Impaired reflexes, impaired balance, and impaired coordination, and dizziness)